Ankylosing spondylitis guidelines, EBSCOhost | | PRIMARY BILIARY CIRRHOSIS AND ANKYLOSING SPONDYLITIS, A RARE ASSOCIATION.
Conținutul
Abstract: Although the relation between periodontitis PD and systemic ankylosing spondylitis guidelines e. We prospectively examined the relationship between periodontal disease and AS, focusing on the rate and course of PD, factors associated with severity and the impact of anti-TNF-a treatment on inflammatory status. More than half of AS presented with impaired periodontal health at baseline mild to moderate PD meaning increased sites with dental plaque, abnormal bleeding, increased periodontal pocket depth and clinical attachment loss.
Significant positive correlation between presence and severity of PD, AS activity and systemic inflammation CRP was reported at baseline p[0. A final analysis performed at 24 weeks revealed significant improvement in periodontal status, inflammatory parameters and AS activity, suggesting efficacy of TNF inhibitors directed not only against systemic, but also on ankylosing spondylitis guidelines articular, periodontal inflammation p[0.
Patients with AS are at risk to develop periodontal disease, ankylosing spondylitis guidelines those with high levels of systemic inflammation. Benefits of anti-TNFa therapy in the particular settings of AS patient and concomitant periodontal disease should be validated through further studies in larger cohorts.